Nicotine Pouches And The Mel Gibson Effect
Nicotine, a chemical most commonly within the plants of the Solanaceae family, can be an alkaloid and is available accumulated in the leaves of these plants, although biosynthesis of the chemical occurs in the roots of the plants. Nicotine is among the major components of addictive plants like tobacco (0.6%-3.0%) and ‘s the reason behind their addiction in humans due to its psychoactive nature.
The follow are 10 interesting factual statements about nicotine.
1. Etymology
The name nicotine originates from the scientific name of the tobacco plant Nicotiana tabacum. The scientific name of the tobacco plant is itself named the French ambassador to Portugal Jean Nicot de Villemain. Villeman is credited for sending tobacco seeds and plant saplings to Paris in 1560 because of its used in medicinal purposes.
2. Extraction
Nicotine was initially extracted from the tobacco plant by German physician Dr. Wilhelm Heinrich Posselt and chemist Karl Ludwig Reimann in 1828. Following its discovery Posselt and Reimann labelled it as a poison. Actually nicotine is an antiherbivore chemical, which in turn causes addiction when consumed in smaller amounts (1mg or less) and death if taken in high amounts (30mg-60mg).
3. Chemistry
Nicotine is an alkaloid with the chemical formula C10H14N2. Its IUPAC name is 3[2,5-1-methylpyrrolidin-2-yl]pyridine. It has a molecular mass of 162.12g/mol. Nicotine is a hygroscopic liquid that is miscible with water as a nitrogenous base. Its density is 1.01g/cm3, melting point -79oC and boiling point 247oC. The nicotine molecule includes a half life of 2 hours and its own metabolism is hepatic. Nicotine is also optically active and has two enantiomeric forms.
4. Nicotine being an insecticide
As already said nicotine is an antiherbivore drug which if used large amounts is fatal alive forms. This is why nicotine laden tobacco has been used as an insecticide even before the World War II. But after the WWII its usage drastically lowered as a result of availability of cheap synthetic insecticides which are more readily available than tobacco and less bad for mammals. But in the recent years the hype surrounding organic farming has again increased the interest of the farmers in the use of tobacco as a pesticide being an alternate to chemical pesticides.
5. Nicotine addiction
Our central nervous system has certain nicotinic acetylcholine receptors. Nicotine binds to several of these and increases the quantity of several neurotransmitters. Among these neurotransmitters dopamine is one particular neurotransmitter that is significantly increased during nicotine use and is responsible for the sense of euphoria and relaxation caused by the use of tobacco (nicotine) products.
6. Psychoactive ramifications of nicotine
Nicotine is a psychoactive substance as it is mood altering. It causes both euphoria and relaxation. Within the body nicotine is metabolised in the liver. First following its metabolism nicotine results in the release of glucose from the liver and epinephrine from the adrenal medulla. This sudden release of glucose and epinephrine causes euphoria following the intake of nicotine. Following the initial euphoria nicotine results in relaxation, increased alertness and sharpness by focusing on different neurotransmitters of your body. Nicotine also offers pain relieving properties.
7. Unwanted effects of nicotine intake
Tough it looks like nicotine is a wonderful substance to increase one’s sharpness, induce calmness and elevate one’s mood you can find more negative areas of nicotine intake than positive. Among these the most typical unwanted effects of nicotine intake are an elevated risk of hypertension and heart attacks. It really is sad that every cigarette that a man smokes reduces his life span by 14 years. Moreover since nicotine has been found to affect the working of Estrogen on hippocampus, hence over time nicotine users are inclined to amnesia and other related diseases.
8. Nikotiinipussit Toxicity
Nicotine is known as to be more toxic than most common drugs like heroin and cocaine. More harm is performed by nicotine to our body since it is readily absorbed by the bloodstream and reaches the mind through the lungs within 7 seconds of its intake either orally or as nicotine patches.
9. Use of nicotine in medical science
Though nicotine is not a doctor’s best friend, it is yet not his worst foe. Nicotine known for its pain relieving properties has been researched upon to be utilized as a potential pain killer minus its harmful effects. Nicotine has also been found to lessen preeclampsia, allergic asthma; among others by acting being an anti-inflammatory agent.
10. Nicotine in literature
Nicotine has been personified in popular literature as Nick O’ Teen, a humanoid villainous character in Superman comics which was created as a part of anti-nicotine drive to educate children about the ill-effects of nicotine intake in any form.
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